Tuesday, June 12, 2012

'K10a' calculator

The 'K10a' calculator represents an intermediate stage between the K7 and K12 analyses released so far from the Project. The following components have been inferred:
  • Palaeoafrican 
  • South_Asian 
  • West_Asian 
  • Southeast_Asian 
  • Sub_Saharan 
  • Atlantic_Baltic
  • Red_Sea 
  • East_Asian 
  • Mediterranean 
  • Siberian 
There are a couple of points of interest; first, the Red_Sea component related Arabians with East Africans. At a higher level of resolution the "Southwest_Asian" and "East_African" (K12)  components emerge. The "Red_Sea" component is not very closely related to any other components, but is somewhat related to the "Mediterranean" and "Atlantic_Baltic" components.

So, using the different calculators of the Dodecad Project, we first have (K7) a contrast between Africa and West Eurasia, then a signal of the shared ancestry between Arabia and East Africa (K10), and finally, strong signals of local ancestry in the two regions.

Second, the Mediterranean component here is modal in Sardinians as usual, but also projects into North Africa. Again, this is intermediate between K7 which shows a predominance of West Eurasian ancestry in North Africa + an African component, and K12 in which there are "Atlantic_Med" and "Northwest_Afican" regional components.

These are strong hints that the West Eurasian element in Africa differs between NW and E Africa. In the former region, it is most related to Sardinians, and in the latter it is most related to Arabians. Of course, ultimately the two elements are related to each other.

Table of Fst distances between components:


MDS plots of the first few dimensions:


Downloads: 
Project participants can find their results in the spreadsheet. Non-participants can use DIYDodecad to calculate their results, but they should place all the calculator files in the same directory as the DIYDodecad software, and replace 'dv3' with 'K10a' in all the instructions of the README file.

Component labels are indicative, and you should compare your results against the normalized median results for different populations included in the spreadsheet.

Terms of Use

You are free to use 'K10a', including all downloaded files for any non-commercial purpose, as long as you attribute them to the Dodecad Project and to Dienekes Pontikos as follows:

The 'K10a' admixture calculator is courtesy of Dienekes Pontikos and was developed as part of the Dodecad Ancestry Project; more information here.

Saturday, June 9, 2012

'weac2' calculator

I have made a new version of the 'weac' calculator (West Eurasian cline). This is based on a large Old World dataset at K=7 and includes the following ancestral components:
  • Palaeoafrican 
  • Atlantic_Baltic 
  • Northeast_Asian 
  • Near_East 
  • Sub_Saharan 
  • South_Asian 
  • Southeast_Asian 

The West Eurasian cline is formed between the Near_East and Atlantic_Baltic components.

Here is the table of Fst distances between components:

MDS plots of the first few dimensions:


Downloads:
Project participants can find their results in the spreadsheet. Non-participants can use DIYDodecad to calculate their results, but they should place all the calculator files in the same directory as the DIYDodecad software, and replace 'dv3' with 'weac2' in all the instructions of the README file.

(NOTE: Some  IDs may have wrong results in the spreadsheet because of a misalignment of IDs with results; I'll fix this and update this notice. UPDATE: Results should be correct in spreadsheet now - 9 Jun 2012)


Component labels are indicative, and you should compare your results against the normalized median results for different populations included in the spreadsheet.

Terms of Use

You are free to use 'weac2', including all downloaded files for any non-commercial purpose, as long as you attribute them to the Dodecad Project and to Dienekes Pontikos as follows:

The 'weac2' admixture calculator is courtesy of Dienekes Pontikos and was developed as part of the Dodecad Ancestry Project; more information here.